Gardner Syndrome

What are the screening options for Gardner syndrome?

The screening options for Gardner syndrome are considered to be similar to those for classic FAP, with the addition of regular dermatologic (skin) examinations.

It is important to discuss with your doctor the following screening options, as each individual is different.

Screening options for classic FAP include:

Yearly screening for hepatoblastoma, from birth to age 5 in children at risk, including a physical examination, abdominal ultrasound, and a blood test to measure alpha-fetoprotein (AFP) levels

Yearly flexible sigmoidoscopy, beginning between the ages of 10 to 12 for children at risk for FAP

Colonoscopy once polyps are detected; individuals with classic FAP will typically need a colectomy (the surgical removal of the entire colon) at some point due to the number of polyps and the high risk ofcolorectal cancer

Upper endoscopy (EGD) every one to three years, beginning at age 25 or after polyps are detected

X-ray or computed tomography (CT or CAT) scan of the small bowel if adenomas are found on EGD or before a colectomy; repeat every one to three years depending on symptoms

Yearly physical examination, including thyroid evaluation

Yearly dermatologic examination of skin (or more frequently if necessary)

Screening options may change over time as new technologies are developed and more is learned about Gardner syndrome. It is important to talk with your doctor about appropriate screening tests.