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Cancer Medicine :: Xeroderma Pigmentosum

Xeroderma Pigmentosum

What are the screening options for XP?

Current suggested screenings for people who are known or suspected to have XP include:

Careful skin examination by a doctor every three to six months

Frequent skin examination by a family member who is familiar with the features of XP-associated skin cancer

Regular eye examinations by an ophthalmologist (a doctor who specializes in the treatment and function of the eye)


Evidence of ultraviolet type mutations in xeroderma pigmentosum melanomas

Routine neurologic evaluation

Due to the high risk of multiple skin cancers, people with XP should avoid sunlight and other UV light exposure, covering the skin completely and wearing UV-absorbing sun glasses when outside. People with XP are also sensitive to UVC rays given off by some artificial light sources. Halogen bulbs and some fluorescent bulbs emit sufficient UV to burn some individuals. 

Screening recommendations may change over time as new technologies are developed and more is learned about XP. It is important to talk with your doctor about appropriate screening tests.

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